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Which of the following statements is correct with reference to enzymes ?

(a) Holoenzyme = Apoenzyme + Coenzyme

(b) Coenzyme = Apoenzyme + Holoenzyme

(c) Holoenzyme = Coenzyme + Co­factor

(d) Apoenzyme = Holoenzyme + Coenzyme
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Ans : (1) Holoenzyme = Apoenzyme + Coenzyme

Explanation :

Holoenzyme is the active form of the enzyme. It is made of 2 components called the apoenzyme and coenzyme. A cofactor can also be a called as a coenzyme if it is an organic molecule. The apoprotein itself is inactive. On binding with the cofactor, it gets activated resulting in the formation of a holoenzyme that is functional.

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