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The separation of two chromatids of each chromosome at early anaphase is initiated by

(a) the interaction of centromere with the chromosomal fibres

(b) the elongation of metaphasic spindle

(c) the force of repulsion between the divided kinetochores

(d) all of these.
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Ans: (c) the force of repulsion between the divided kinetochores

Explanation: Anaphase is the stage of mitosis after the metaphase when replicated chromosomes are split and the daughter chromatids are moved to opposite poles of the cell. The separation of two chromatids of each chromosome at early anaphase is initiated by the force of repulsion between the divided kinetochores. Kinetochores are a protein which forms a complex with centromere of a chromosome during cell division.

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